Evolutionary Glycomics: Characterization of Milk Oligosaccharides in Primates
نویسندگان
چکیده
منابع مشابه
Evolutionary glycomics: characterization of milk oligosaccharides in primates.
Free oligosaccharides are abundant components of mammalian milk and have primary roles as prebiotic compounds, in immune defense, and in brain development. A mass spectrometry-based technique is applied to profile milk oligosaccharides from apes (chimpanzee, gorilla, and siamang), new world monkeys (golden lion tamarin and common marmoset), and an old world monkey (rhesus). The purpose of this ...
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Two new octasaccharides were isolated from human milk of a nonsecretor Lewis a+bindividual. Structural studies by sequential enzymic degradation and by quantitative methylation analysis revealed that their structures were as follows: Gal/31 + 3 (Fuccul + 4) GlcNAcPl + 3Gal/H -+ 4 (Fucal -+ 3) GlcNAcPl + 3Gal/31+ 4Glc, Gal/?1 + 4 (Fuccul -+ 3) GlcNAcj31 + 3Gal/31 -+ 4 (Fuccul -+ 3) GlcNAcj31 + 3...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2011
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr1009367